Publications


Cell cycle arrest induces lipid droplet formation and confers ferroptosis resistance


Hyemin Lee, Amber Horbath, Lavanya Kondiparthi, Jitendra Kumar Meena, Guang Lei, Shayani Dasgupta, Xiaoguang Liu, Zhuang Li, Pranavi Koppula, Mi Li, Iqbal Mahmud, Bo Wei, Philip L. Lorenzi, K. Keyomarsi, M. Poyurovsky, Kellen L. Olszewski, B. Gan

Nature Communications, 2024


Spliceosome-targeted therapies trigger an antiviral immune response in triple-negative breast cancer


Elizabeth A. Bowling, Jarey H. Wang, Fade Gong, William Wu, N. Neill, I. Kim, S. Tyagi, Mayra Orellana, S. Kurley, Rocio Dominguez Vidana, Hsiang-Ching Chung, T. Hsu, Julien Dubrulle, Alexander B. Saltzman, Heyuan Li, Jitendra Kumar Meena, Gino M. Canlas, S. Chamakuri, Swarnima Singh, L. Simon, C. Olson, L. Dobrolecki, M. Lewis, Bing Zhang, I. Golding, J. Rosen, D. Young, A. Malovannaya, F. Stossi, G. Miles, M. Ellis, Lihua Yu, S. Buonamici, Charles Y. Lin, Kristen L. Karlin, X. Zhang, Thomas F. Westbrook

Cell, 2021


Inhibition of YTHDF2 triggers proteotoxic cell death in MYC-driven breast cancer.


J. Einstein, M. Perelis, I. A. Chaim, Jitendra Kumar Meena, Julia K. Nussbacher, Alexandra T. Tankka, Brian A. Yee, Heyuan Li, Assael A. Madrigal, N. Neill, Archana Shankar, S. Tyagi, Thomas F. Westbrook, Gene W. Yeo

Molecules and Cells, 2021


Energy-stress-mediated AMPK activation inhibits ferroptosis


Hyemin Lee, F. Zandkarimi, Yilei Zhang, Jitendra Kumar Meena, Jongchan Kim, L. Zhuang, S. Tyagi, Li Ma, Thomas F. Westbrook, G. Steinberg, Daisuke Nakada, B. Stockwell, B. Gan

Nature Cell Biology, 2020


Aneuploidy-inducing gene knockdowns overlap with cancer mutations and identify Orp3 as a B-cell lymphoma suppressor


Sospeter N. Njeru, J. Kraus, Jitendra Kumar Meena, A. Lechel, Sarah-Fee Katz, Mukesh Kumar, U. Knippschild, A. Azoitei, F. Wezel, C. Bolenz, F. Leithäuser, André Gollowitzer, O. Omrani, C. Hoischen, A. Koeberle, H. Kestler, C. Günes, K. Rudolph

Oncogene, 2019


Telomerase abrogates aneuploidy-induced telomere replication stress, senescence and cell depletion


Jitendra Kumar Meena, A. Cerutti, Christine Beichler, Yohei Morita, Christopher Bruhn, Mukesh Kumar, J. Kraus, M. Speicher, Zhao-Qi Wang, H. Kestler, F. d’Adda di Fagagna, C. Günes, K. Rudolph

EMBO Journal, 2015


Telomere Dysfunction, Chromosomal Instability and Cancer.


Jitendra Kumar Meena, K. Rudolph, C. Günes

Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 2015


Telomerase stimulates ribosomal DNA transcription under hyperproliferative conditions


Omar García González, R. Assfalg, S. Koch, Adrian Schelling, Jitendra Kumar Meena, J. Kraus, A. Lechel, Sarah-Fee Katz, V. Beneš, K. Scharffetter-Kochanek, H. Kestler, C. Günes, S. Iben

Nature Communications, 2014


CEBP factors regulate telomerase reverse transcriptase promoter activity in whey acidic protein‐T mice during mammary carcinogenesis


Mukesh Kumar, B. Witt, U. Knippschild, S. Koch, Jitendra Kumar Meena, Christina Heinlein, J. Weise, Frauke Krepulat, F. Kuchenbauer, S. Iben, K. Rudolph, W. Deppert, C. Günes

International Journal of Cancer, 2013


Human telomerase reverse transcriptase promoter is activated during liver regeneration and hepatocyte proliferation


H. Sirma, Mukesh Kumar, Jitendra Kumar Meena, B. Witt, J. Weise, A. Lechel, Satyanarayana Ande, V. Sakk, C. Guguen-Guillouzo, L. Zender, K. Rudolph, C. Günes

2012


The promoter of human telomerase reverse transcriptase is activated during liver regeneration and hepatocyte proliferation.


H. Sirma, Mukesh Kumar, Jitendra Kumar Meena, B. Witt, J. Weise, A. Lechel, Satyanarayana Ande, V. Sakk, C. Guguen-Guillouzo, L. Zender, K. Rudolph, C. Günes

Gastroenterology, 2011

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